real science. real results.

Addyi is the first and only FDA-approved pill for frustrating low libido, proven to increase sex drive in BOTH premenopausal and postmenopausal women (<65).

real science. real results.

Addyi is the first and only FDA-approved pill for frustrating low libido, proven to increase sex drive in BOTH premenopausal and postmenopausal women (<65).

In clinical trials, women on Addyi experienced*:

More interest in Sex

Less Stress (from frustrating low libido)

More Satisfying Sex**

*Efficacy of Addyi was established in three 24-week trials in over 2,000 women with acquired, generalized HSDD. Patients were treated with Addyi (n=1187) or placebo (n=1188). Not all women will experience similar improvement in their HSDD.
**Increased in number of times per month.

In clinical trials, women on Addyi experienced*:

More interest in Sex

Less Stress (from frustrating low libido)

More Satisfying Sex**

*Efficacy of Addyi was established in three 24-week trials in over 2,000 women with acquired, generalized HSDD. Patients were treated with Addyi (n=1187) or placebo (n=1188). Not all women will experience similar improvement in their HSDD.
**Increased in number of times per month.

Taking Addyi

Take one (1) 100mg tablet of Addyi daily at bedtime as directed by your healthcare professional. Some women may start to notice the effects of Addyi within a few weeks; others may start to notice an increase in sexual desire or a decrease in distress after 4 to 8 weeks of nightly use.*

*Some women may see results in as early as 4 weeks. Addyi should be discontinued if there is no improvement after 8 weeks.

Taking Addyi

Take one (1) 100mg tablet of Addyi daily at bedtime as directed by your healthcare professional. Some women may start to notice the effects of Addyi within a few weeks; others may start to notice an increase in sexual desire or a decrease in distress after 4 to 8 weeks of nightly use.*

*Some women may see results in as early as 4 weeks. Addyi should be discontinued if there is no improvement after 8 weeks.

How Addyi Works

Addyi is non hormonal — it works in the brain. Addyi is believed to rebalance brain chemicals related to desire. Addyi increases the brain chemicals that enhance interest in sex, while reducing the ones that might be dampening desire.

Tracking Your Addyi Progress

Some prescribers recommend a daily journal or app for keeping track of changes in desire, frequency of satisfying sexual events and distress or frustration due to low desire.

How Addyi Works

Addyi is non hormonal — it works in the brain. Addyi is believed to rebalance brain chemicals related to desire. Addyi increases the brain chemicals that enhance interest in sex, while reducing the ones that might be dampening desire.

Tracking Your Addyi Progress

Some prescribers recommend a daily journal or app for keeping track of changes in desire, frequency of satisfying sexual events and distress or frustration due to low desire.

Early Signs Addyi is Working

You think about sex more often

  • You find yourself thinking about sex more often than you used to.
  • Sexual thoughts or daydreams come up more easily, and without having to force it.
  • You feel more receptive to the idea of initiating sex, or being receptive when a partner initiates.

You experience more enjoyment during sexual activity

  • As your desire improves, you may begin to notice that you want sex more often.

You have less stress around sex

  • You may experience a decrease in stress or avoidance around sex.
  • You may feel less indifferent around the idea of sex.

Early Signs Addyi is Working

You think about sex more often

  • You find yourself thinking about sex more often than you used to.
  • Sexual thoughts or daydreams come up more easily, and without having to force it.
  • You feel more receptive to the idea of initiating sex, or being receptive when a partner initiates.

You experience more enjoyment during sexual activity

  • As your desire improves, you may begin to notice that you want sex more often.

You have less stress around sex

  • You may experience a decrease in stress or avoidance around sex.
  • You may feel less indifferent around the idea of sex.

Start a telemedicine visit today to see if Addyi is right for you.

The exact mechanism of action of Addyi is unknown.

Before You Begin

The most common side effects of Addyi include dizziness, nausea, tiredness, difficulty falling asleep or staying asleep and dry mouth.

In the evening if you consume up to 2 drinks§ wait 2 hours before taking Addyi at bedtime; skip your Addyi dose if you have consumed 3 or more drinks§ that evening.

§ A standard alcoholic drink includes: one 12-ounce regular beer, 5 ounces of wine, 1.5 ounces of distilled spirits or shot.

Before You Begin

The most common side effects of Addyi include dizziness, nausea, tiredness, difficulty falling asleep or staying asleep and dry mouth.

In the evening if you consume up to 2 drinks§ wait 2 hours before taking Addyi at bedtime; skip your Addyi dose if you have consumed 3 or more drinks§ that evening.

§ A standard alcoholic drink includes: one 12-ounce regular beer, 5 ounces of wine, 1.5 ounces of distilled spirits or shot.

INDICATION AND IMPORTANT SAFETY INFORMATION

INDICATION

What is ADDYI (add-ee) (flibanserin) Tablets?
ADDYI is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women <65 years of age who have not had problems with low sexual desire in the past, and who have low sexual desire no matter the type of sexual activity, the situation, or the sexual partner. Women with HSDD have low sexual desire that is troubling to them. Their low sexual desire is not due to:

  • a medical or mental health problem
  • problems in the relationship
  • medicine or other drug use.

ADDYI is not for use in men or in children, or to improve sexual performance.

IMPORTANT SAFETY INFORMATION
What is the most important information I should know about ADDYI?
Your risk of severe low blood pressure and fainting (loss of consciousness) is increased:

  • if you drink alcohol close to the time you take your ADDYI dose,
  • if you take ADDYI with certain medicines, or
  • if you have liver problems and you take ADDYI.

To lower your risk of low blood pressure and fainting (loss of consciousness):

  • Do not drink alcohol close to the time you take your ADDYI dose
    • Wait at least 2 hours after drinking 1 or 2 standard alcoholic drinks before taking ADDYI at bedtime.
    • Skip your ADDYI dose if you drink 3 or more standard alcoholic drinks that evening.
  • After taking ADDYI at bedtime do not drink alcohol until the following day.

Tell your doctor about other medicines you take. Do not take or start taking any prescription or over-the-counter medicines, or herbal supplements without first talking to your doctor.
Do not take ADDYI if you have liver problems.
If you take Addyi and feel lightheaded or dizzy, lie down right away. Call for help if the symptoms do not go away.

Who should not take ADDYI?
Do not take ADDYI if you:

  • take certain medicines. Taking ADDYI with certain other medicines can increase the amount of ADDYI in your blood and cause severe low blood pressure, fainting (loss of consciousness), and sleepiness.
  • Do not take ADDYI if you are taking any of the following: certain medicines to treat HIV-1 infection, fungal infections, antibiotics, Hepatitis C infection, high blood pressure, chest pain (angina), or other heart problems, nefazodone used to treat depression.
  • have liver problems

What should I tell my doctor before taking ADDYI?
Before you take ADDYI, tell your doctor about all of your medical conditions, including if you:

  • drink alcohol, use drugs, or have a history of alcohol or drug abuse
  • have ever had depression or other mental health problems
  • have low blood pressure or a medical condition that can cause low blood pressure
  • are pregnant or plan to become pregnant. It is not known if ADDYI will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if ADDYI passes into your breast milk. You and your doctor should decide if you will take ADDYI or breastfeed. You should not do both.

Tell your doctor if you have had an allergic reaction such as hives, itching, or trouble breathing during or after receiving a dose of ADDYI.
Tell your doctor about all of the medicines you take, ADDYI can affect the way other medicines work, and other medicines can affect the way ADDYI works, and can cause serious side effects.

What should I avoid while taking ADDYI?

  • Do not drink alcohol close to the time you take your ADDYI dose.
  • Do not drive, operate machinery, or do things that require clear thinking until at least 6 hours after you take ADDYI and until you know how ADDYI affects you.
  • Do not drink grapefruit juice if you take ADDYI. Drinking grapefruit juice during your treatment with ADDYI increases your risk of severe low blood pressure and fainting (loss of consciousness).
  • You should not take the herbal supplements St. John’s Wort, ginkgo, or resveratrol or certain over-the-counter medicines such as cimetidine until you talk to your doctor. Taking with ADDYI may increase your risk of low blood pressure, fainting (loss of consciousness), and sleepiness.

What are the possible side effects of ADDYI?
ADDYI can cause serious side effects, including:

  • Sleepiness is a common side effect of ADDYI and can be serious.
  • Low blood pressure and fainting (loss of consciousness) can happen when you take ADDYI even if you do not drink alcohol or take other medicines or herbal supplements.

Your risk of sleepiness, low blood pressure and fainting is increased if ADDYI is taken during waking hours, if you drink alcohol (risk of low blood pressure and fainting is increased within 2 hours of taking ADDYI), or take certain medicines or herbal supplements.

The most common side effects of ADDYI include:

  • Dizziness
  • Difficulty falling asleep or staying asleep
  • Nausea
  • Dry mouth
  • Tiredness

These are not all of the possible side effects of ADDYI. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

See full Prescribing Information, including Boxed Warning regarding severe low blood pressure and fainting in certain settings, and Medication Guide at addyi.com/pi.